Prednisone (Glucocorticoid, Corticosteroid) is used to stop inflammatory processes, an allergic reaction of the body. The tool helps to cope with itching, has an anti-exudative effect. Shortly after the penetration of the active compound into the human body, the following is observed: the formation and release of inflammatory mediators is controlled and inhibited. Prednisone affects kinin and histamine and controls the activity of lysosomal enzyme compounds. Under its influence, cells cannot move freely to the inflammatory focus. Prednisone reduces the permeability of the vascular walls in the area of localization of the inflammatory process, and inhibits vasodilation.
Exudation when using Prednisone ointment (as well as tablets or ampoules) becomes less active. The process is due to the vasoconstrictor effect. The main compound of the drug is able to inhibit macrophages, cytokines, reduce the activity of target cells. Thus, it is possible to control all the elements of the body that take part in the development of contact dermatitis provoked by an allergic reaction. Under the influence of Prednisone, target cells are protected from the effects of macrophages, T-lymphocytes that have undergone sensitization.